Insights into the Progression of Labile Hb A1c to Stable Hb A1c via a Mechanistic Assessment of 2,3-Bisphosphoglycerate Facilitation of the Slow Nonenzymatic Glycation Process
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چکیده
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15 صفحه اولThe role and quality of hb a1c: a continuing evolution.
Since glycohemoglobin was first described in the red cells of diabetes patients in 1968 (1 ), the test has evolved to become an essential tool for prognosis, monitoring, treatment, and diagnosis of diabetes mellitus. An increasing clinical focus together with the development of diabetes management guidelines based on glycated hemoglobin (Hb A1c) 2 necessitated a standardization of the method in...
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SUMMARY: At present, measurment of glycosylated hemoglobin, especially the stable fraction of hemoglobin (HbA1c) is one of the ways to control diabetes because this measurment can demonstrate total glycemia during last 1.2.3 months. Glycosylated hemoglobin is seen in 3 forms: Ala Alb A1c. Among these hemoglobin Alc is quantitively more than other 2 forms and its difference with other hemoglobi...
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Progression of nephropathy in type 2 diabetes: the glycation gap is a significant predictor after adjustment for glycohemoglobin (Hb A1c).
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ژورنال
عنوان ژورنال: Hemoglobin
سال: 2019
ISSN: 0363-0269,1532-432X
DOI: 10.1080/03630269.2019.1597731